KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
36.06
Human Site:
S611
Identified Species:
66.11
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S611
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S611
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
C571
Y
I
Y
M
V
M
E
C
G
N
I
D
L
N
S
Dog
Lupus familis
XP_539016
855
96614
S608
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
S610
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
Rat
Rattus norvegicus
NP_001101642
835
94323
S589
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
S622
C
G
N
I
D
L
N
S
W
L
R
K
K
K
T
Chicken
Gallus gallus
XP_419867
879
99691
S628
C
G
N
I
D
L
N
S
W
L
K
K
K
R
N
Frog
Xenopus laevis
NP_001082090
882
99060
T632
C
G
N
I
D
L
N
T
W
L
R
K
K
K
T
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
T739
C
G
H
L
D
L
N
T
W
L
R
N
R
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
N598
H
S
D
L
K
P
A
N
F
L
L
V
K
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
G570
F
L
K
L
I
D
F
G
I
A
K
A
I
N
S
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
A557
C
I
K
V
V
H
D
A
G
I
V
H
S
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
86.6
86.6
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
8
0
8
0
0
0
% A
% Cys:
77
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
70
8
8
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
70
0
0
0
0
0
8
16
0
0
0
0
8
0
% G
% His:
8
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
16
0
62
8
0
0
0
8
8
8
0
8
0
0
% I
% Lys:
0
0
16
0
8
0
0
0
0
0
54
62
70
62
0
% K
% Leu:
0
8
0
24
0
70
0
0
0
77
8
0
8
0
8
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
62
0
0
0
70
8
0
8
0
8
0
16
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
24
0
8
8
0
% R
% Ser:
0
8
0
0
0
0
0
54
0
0
0
0
8
0
62
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
24
% T
% Val:
0
0
0
8
16
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _